Attila Hunyadi Selected Research

Ecdysteroids

1/2023	Highly Oxidized Ecdysteroids from a Commercial Cyanotis arachnoidea Root Extract as Potent Blood-Brain Barrier Protective Agents.
1/2020	Squalenoylated Nanoparticle Pro-Drugs of Adjuvant Antitumor 11α-Hydroxyecdysteroid 2,3-Acetonides Act as Cytoprotective Agents Against Doxorubicin and Paclitaxel.
5/2018	Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance.
1/2018	Nitrogen-containing ecdysteroid derivatives vs. multi-drug resistance in cancer: Preparation and antitumor activity of oximes, oxime ethers and a lactam.
1/2017	Backstabbing P-gp: Side-Chain Cleaved Ecdysteroid 2,3-Dioxolanes Hyper-Sensitize MDR Cancer Cells to Doxorubicin without Efflux Inhibition.
1/2017	BBB penetration-targeting physicochemical lead selection: Ecdysteroids as chemo-sensitizers against CNS tumors.
1/2015	Ecdysteroids sensitize MDR and non-MDR cancer cell lines to doxorubicin, paclitaxel, and vincristine but tend to protect them from cisplatin.
12/2013	Synthesis and structure-activity relationships of novel ecdysteroid dioxolanes as MDR modulators in cancer.
6/2012	Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter.

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Attila Hunyadi Research Topics

Disease

20	Neoplasms (Cancer) 04/2024 - 06/2012
4	Lymphoma (Lymphomas) 01/2021 - 01/2015
3	Ataxia Telangiectasia (Louis Bar Syndrome) 09/2023 - 07/2012
2	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 01/2024
1	Triple Negative Breast Neoplasms 09/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023
1	Melanoma (Melanoma, Malignant) 11/2020
1	Virus Diseases (Viral Diseases) 03/2020
1	Burkitt Lymphoma (Burkitt's Lymphoma) 03/2020
1	Insulin Resistance 03/2019
1	Inflammation (Inflammations) 03/2019
1	Genomic Instability 03/2019
1	Chronic Disease (Chronic Diseases) 03/2019
1	Carcinoma (Carcinomatosis) 01/2019
1	Neuroblastoma 01/2017
1	Breast Neoplasms (Breast Cancer) 11/2016
1	Hypoxia (Hypoxemia) 09/2015
1	Type 2 Diabetes Mellitus (MODY) 02/2014
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2013
1	Pulmonary Tuberculosis 12/2013
1	Tuberculosis (Tuberculoses) 01/2013
1	Bacterial Infections (Bacterial Infection) 01/2013
1	Chromosome Aberrations (Chromosome Abnormalities) 07/2012
1	T-Cell Lymphoma (Lymphoma, T Cell) 06/2012
1	Vitamin D Deficiency 01/2010

Drug/Important Bio-Agent (IBA)

9	EcdysteroidsIBA 01/2023 - 06/2012
8	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2022 - 06/2012
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 04/2022 - 09/2015
4	protoapigenoneIBA 11/2020 - 07/2012
3	Proteins (Proteins, Gene)FDA Link 09/2023 - 03/2020
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 07/2012
3	Cisplatin (Platino)FDA LinkGeneric 11/2016 - 07/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2020 - 01/2019
2	NitrogenIBA 01/2018 - 09/2015
2	Vincristine (Oncovin)FDA LinkGeneric 01/2017 - 01/2015
1	AbietanesIBA 04/2024
1	DiterpenesIBA 04/2024
1	royleanoneIBA 04/2024
1	hydroquinone (Esoterica)FDA Link 04/2024
1	EstersIBA 01/2024
1	thymoquinoneIBA 01/2024
1	AzidesIBA 09/2023
1	spirooxindoleIBA 09/2023
1	Alkynes (Acetylenes)IBA 09/2023
1	CopperIBA 09/2023
1	2-oxindole (oxindole)IBA 09/2023
1	Antineoplastic Agents (Antineoplastics)IBA 01/2023
1	Organophosphorus CompoundsIBA 12/2021
1	protoapigenone 1'-O-butyl etherIBA 11/2020
1	HydroquinonesIBA 11/2020
1	Chalcone (Benzalacetophenone)IBA 06/2020
1	ferroceneIBA 06/2020
1	PhytochemicalsIBA 03/2020
1	SqualeneIBA 01/2020
1	ProdrugsIBA 01/2020
1	PolyphenolsIBA 03/2019
1	Glucose (Dextrose)FDA LinkGeneric 03/2019
1	SirtuinsIBA 03/2019
1	QuercetinIBA 03/2019
1	OximesIBA 01/2018
1	LactamsIBA 01/2018
1	EthersIBA 01/2018
1	FlavonoidsIBA 11/2016
1	Etoposide (VP 16)FDA LinkGeneric 11/2016
1	Glutathione (Reduced Glutathione)IBA 09/2015
1	Oxygen (Dioxygen)IBA 09/2015
1	Superoxide DismutaseIBA 09/2015
1	Glutathione Transferase (Glutathione S-Transferase)IBA 09/2015
1	Ecdysterone (20 Hydroxyecdysone)IBA 01/2015
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2015
1	GlycosidesIBA 02/2014
1	DioxolanesIBA 12/2013
1	phenothiazineIBA 12/2013
1	Thioridazine (Mellaril)FDA LinkGeneric 12/2013
1	Phosphotransferases (Kinase)IBA 07/2012
1	EcdysoneIBA 06/2012
1	Vitamin D FDA LinkGeneric 01/2010

Therapy/Procedure

4	Therapeutics 11/2020 - 01/2013
4	Drug Therapy (Chemotherapy) 01/2017 - 06/2012